THE IMPACT OF GLOBAL FALSIFIED MEDICINES REGULATION ON HEALTHCARE STAKEHOLDERS IN THE LEGITIMATE PHARMACEUTICAL SUPPLY CHAIN: A SYSTEMATIC REVIEW

The impact of global falsified medicines regulation on healthcare stakeholders in the legitimate pharmaceutical supply chain: a systematic review

BackgroundFalsified medicines and their international regulation impacts all healthcare sectors and their actors.These regulations aim to strengthen and protect the global pharmaceutical supply chain against falsified medicines.However, an evaluation of the impacts of these regulations on key stakeholders within the legitimate supply chain have not

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PhotoGal4: A Versatile Light-Dependent Switch for Spatiotemporal Control of Gene Expression in Drosophila Explants

Summary: We present here PhotoGal4, a phytochrome B-based optogenetic switch for fine-tuned spatiotemporal control of gene expression in Drosophila explants.This switch integrates the light-dependent interaction between phytochrome B and PIF6 from EHF plants with regulatory elements from the yeast Gal4/UAS system.We found that PhotoGal4 efficiently

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Increase of Neisseria meningitidis W:cc11 invasive disease in Chile has no correlation with carriage in adolescents.

Neisseria meningitidis is a human exclusive pathogen that can lead to invasive meningococcal disease or may be carried in the upper respiratory tract without symptoms.The relationship between carriage and disease remains poorly understood but it is widely accepted that decreasing carriage by immunization should lead to a reduction of invasive cases

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